In 1947, the Department of the Central Asian Mining District of the General Directorate of State Mining Control under the Council of Ministers of the SSR was established, and later it was perfected into the State Committee for the Control of Safe Conduct of Work in Industry and Mining of the Uzbek SSR (Gosgortekhnadzor UzSSR).

After the independence of the Republic of Uzbekistan in 1991, the State Committee to control the safe conduct of work in the industry and mining of the Uzbek SSR based on the decision of the Cabinet of Ministers of the Republic of Uzbekistan No. 17 dated January 10, 1996 was renamed to the State Committee to monitor the safe conduct of work in mining.

Pursuant to the decree of the President of the Republic of Uzbekistan dated February 07, 2000 No. UP-2535, the State Committee for Controlling the Safe Conduct of Work in Industry and Mining of the Republic of Uzbekistan was transformed into the "Industrial Control" Agency.
In accordance with the Decree of the President of the Republic of Uzbekistan No. PF-3454 dated July 9, 2004, in order to further improve the management structure in the industry, gas supply and mining control and to ensure the effectiveness of monitoring the safe conduct of work, the safety of work in industry and mining The agency of the Republic of Uzbekistan for monitoring the safe conduct of work in the industry, mining and communal-household sector was transformed into the state inspection.

In accordance with the decision of the President of the Republic of Uzbekistan No. 1396 "On measures to further increase the efficiency of the system of organization and conduct of geological exploration work", control of the safe conduct of work in the industry, mining and communal-household sector. Inspection ("Industrial Control Inspection" under the Cabinet of Ministers of the Republic of Uzbekistan) was reorganized into State Inspection ("Industrial Control Inspection" "Industry Control Inspection" under the Cabinet of Ministers of the Republic of Uzbekistan) , the Department of State Control over Geological Research of the Earth's Depth under the State Committee of Geology and Mineral Resources of the Republic of Uzbekistan was transferred to its composition.

Decree No. PF-5594 of the President of the Republic of Uzbekistan dated December 12, 2018 "On measures to radically improve the state management and control system in the field of industrial, radiation and nuclear safety", Decree of the President of the Republic of Uzbekistan dated December 12, 2018 Decision No. PQ-4058 "On the organization of the activities of the State Committee for Industrial Safety of the Republic of Uzbekistan" and the Resolution of the Cabinet of Ministers of the Republic of Uzbekistan dated February 1, 2019 "The State Committee for Industrial Safety of the Republic of Uzbekistan to The State Committee for Industrial Safety was established based on the decision No. 75 "On approval of the regulation on